TODAY今日发布CircCardiovascIntervMay01,:13(5)今日发布01篇（共计03篇）Neuromodulation:TechnologyattheNeuralInterfaceEarlyRecent,Apr28,今日发布01篇CATHETERCARDIOINTEEarlyRecent,Apr28,今日发布01篇JACCMay05,:75(17),-今日发布25篇JACC:HeartFailureMay01,:8(5),-今日发布15篇PediatricTransplantationMay01,:24(3),e今日发布28篇AMJHYPERTENSMay01,:33(5)今日发布15篇ESCHeartFailureEarlyRecent,Apr29,今日发布01篇EuropeanJournalofHeartFailureEarlyRecent,Apr29,今日发布01篇CirculationResearchEarlyRecent,Apr29,今日发布02篇RECOMMEND推荐阅读01高钠饮食对健康青年血压变异性的影响AMJHYPERTENSKamilaUMigdal,MatthewCBabcock,etc.7小时前等18用户推荐阅读本文Highsodium(Na)intakeaugmentsbloodpressurevariability(BPV)innormotensiverodents,withoutchangesinrestingbloodpressure(BP).AugmentedBPVisassociatedwithend-organdamageandcardiovascularmorbidity.ItisunknownifchangesindietaryNainfluenceBPVinhumans.WetestedthehypothesisthathighNafeedingwouldaugmentBPVinhealthyadults.高钠摄入可增加血压正常啮齿动物的血压变异性（BPV），而不改变静息血压（BP）。BPV增高与终末器官损害和心血管疾病发病率有关。目前尚不清楚饮食中Na的变化是否会影响人类的BPV。我们验证了高Na喂养会增加健康成人BPV的假设。Twenty-oneparticipants(10F/11M;26±5years;BP:±11/62±7mmHg)underwentarandomized,controlledfeedingstudythatconsistedof10daysoflow(2.6g/day),medium(6.0g/day),andhigh(18.0g/day)saltdiets.Ontheninthdayofeachdiet,24-hurinesampleswerecollectedandBPVwascalculatedfrom24-hambulatoryBPmonitoring.Onthetenthday,in-laboratorybeat-to-beatBPVwascalculatedduring10minofrest.Serumelectrolyteswereassessed.Wecalculatedaveragerealvariability(ARV)andstandarddeviation(SD)asmetricsofBPV.Asasecondaryanalysis,wecalculatedcentralBPVfromthe24-hambulatoryBPmonitoring.21名受试者（10f/11m；26±5年；血压：±11/62±7mMHg）接受随机对照喂养研究，包括10天低盐饮食（2.6g/天）、中盐饮食（6.0g/天）和高盐饮食（18.0g/天）。在每餐第9天，采集24小时尿标本，通过24小时动态血压监测计算BPV。第10天，在实验室中计算休息10分钟时的血压。测定血清电解质。我们计算了平均实际变异性（ARV）和标准差（SD）作为BPV的指标。作为二次分析，我们根据24小时动态血压监测计算中心血压。24-hurinaryNaexcretion(low=41±24,medium=97±43,high=±92mmol/24h,P0.01)andserumNa(low=.0±2.1,medium=.7±2.7,high=.7±2.5mmol/l,P=0.)increasedwithgreatersaltintake.24-hambulatoryARV(systolicBPARV:low=9.5±1.7,medium=9.5±1.2,high=10.0±1.9mmHg,P=0.37)andbeat-to-beatARV(systolicBPARV:low=2.1±0.6,medium=2.0±0.4,high=2.2±0.8mmHg,P=0.46)werenotdifferent.24-hambulatorySD(systolicBP:P=0.29)andbeat-to-beatSD(systolicBP:P=0.47)werenotdifferent.Therewasatrendforamaineffectofthediet(P=0.08)for24-hambulatorycentralsystolicBPV.24小时尿Na排泄量（低=41±24，中=97±43，高=±92mmol/24小时，P0.01）和血清Na（低=.0±2.1，中=.7±2.7，高=.7±2.5mmol/l，P=0.）随盐摄入量的增加而增加。24小时动态ARV（收缩压ARV:low=9.5±1.7，medium=9.5±1.2，high=10.0±1.9mmHg，P=0.37）和beat-to-beatARV（收缩压ARV:low=2.1±0.6，medium=2.0±0.4，high=2.2±0.8mmhg，P=0.46）无差异。24小时动态血压（收缩压：P=0.29）和逐搏血压（收缩压：P=0.47）无差异。24小时动态中心收缩期BPV饮食的主要影响有一个趋势（P=0.08）。TendaysofhighsodiumfeedingdoesnotaugmentperipheralBPVinhealthy,adults.10天高钠喂养不会增加健康成人外周血BPV。NCT.NCT。TheAmericanHeartAssociationre
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